2,4-Dichlorobutyrophenone stands out as a specialized chemical compound that often finds a home in research and industrial labs. Described by its molecular formula C10H10Cl2O, this organic substance features a phenone backbone bonded to a butyryl group carrying two chlorine atoms at the ortho and para positions. A clear look at the structure shows a benzene ring anchored to a butyrophenone chain with chlorines at the 2 and 4 positions, making it distinctly different from other simple phenones. The CAS number identifies the precise molecular identity in global trade and regulatory systems.
Material scientists categorize 2,4-Dichlorobutyrophenone by its distinct physical form and consistency. Usually, the compound appears as a crystalline solid under room conditions. Some batches display a light yellow tint, though well-purified samples tend toward a nearly white crystal. Flakes, fine powder, irregular pearls, and sometimes even a highly compacted mass may show up, depending on preparation methods and storage humidity. The density often hovers around 1.22 g/cm³—substantially heavier than water—requiring proper weighing for accurate solution preparations. The melting point can range from about 44°C to 46°C, making the substance stable and solid at standard laboratory temperatures. Its molecular weight checks in at 217.1 g/mol, often referenced by chemists during stoichiometry calculations or when preparing custom solutions.
Taking a closer look at chemical behavior, 2,4-Dichlorobutyrophenone carries both polar and nonpolar domains. The benzene ring supplies aromatic stability, while the butyryl side chain offers a flexible handle for chemical modifications. Chlorine atoms at the 2 and 4 positions increase its reactivity in halogen exchange reactions, boosting versatility as a raw material. This compound resists hydrolysis in neutral water but dissolves well in common organic solvents, such as ethanol, chloroform, and dichloromethane. In labs where purity drives results, buyers ask for high-performance liquid chromatography, melting point test, and an analysis of residual solvents. The specification sheet lists purity often above 98%, moisture content below 0.5%, and a residual solvent trace well within global safety limits. With the correct HS Code—291450, covering halogenated ketones in global customs—freight and import/export teams can process shipments smoothly.
Researchers reach for 2,4-Dichlorobutyrophenone when seeking predictable chemical pathways. It performs as a vital intermediate in active pharmaceutical ingredient synthesis, dropping in as a building block during heterocycle formation. Industrial operators rely on it for certain agri-chemical and specialty polymer syntheses. Lab practice frequently sees the solid weighed out, combined with chosen reagents, then dissolved into exact liter volumes of solvent to generate targeted reaction mixtures. Its ability to introduce halogenated fragments helps drive chemical innovation in medicinal chemistry, crop protection, and material science. Reliable performance rests on consistent physical form, purity, and handling.
Safety in handling and transport always deserves top priority. 2,4-Dichlorobutyrophenone may cause skin or eye irritation if spilled or exposed without gloves and goggles. Its dust, if inhaled, presents hazards similar to other fine organic powders—workers need properly rated masks and ventilation, especially in confined prep areas. Direct ingestion poses real health risks, so strict labeling and storage away from food or drink ensure safety. Material Safety Data Sheets assign hazard pictograms and outline emergency procedures. Leaks or accidental spills should be cleaned promptly using absorbent material, then disposed of according to chemical waste rules. I have seen laboratories adopt color-coded secondary containers, making it clear to everyone which products require cautious handling. With careful attention to SOPs and regular staff training, the risks from this potent material can be kept under control.
Warehouses store 2,4-Dichlorobutyrophenone in sealed drums or amber glass bottles, shielding it from light and environmental moisture. Exposure to direct sunlight or water may degrade product quality through slow hydrolysis or de-chlorination. Drums receive unique batch numbers and HS Codes at every point of the supply chain—tracking movement proves essential, especially for inventory control and rapid recall, if needed. Specialists design secondary containment in liquid storage areas, anticipating potential leaks or spills that could harm workers or the ecosystem nearby. Cleanup specialists dispose of waste only in certified hazardous material facilities, recognizing that improper disposal might contaminate ground or water with persistent organo-chlorine residues. Regulatory agencies worldwide continue to update best practices for handling and disposal, and companies that follow those recommendations cut liability and limit environmental impact.
Meeting exacting standards protects both reputation and health. Trained staff perform batch analyses with infrared spectroscopy and gas chromatography before packaging, confirming no unexpected byproducts. Regulatory inspectors check safety protocols, confirm correct documentation under international chemical conventions, and sometimes test samples for banned impurities. Firms that supply 2,4-Dichlorobutyrophenone monitor updates from global agencies like REACH and OSHA. Full transparency in the specification sheet—covering purity, melting point, appearance, package type, shelf life, and HS Code—builds trust. Through direct, repeated engagement with suppliers and users, better communication shapes a safety culture that keeps incidents rare and confidence in supply high.
