tert-Butyl (4R-cis)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate stands out in the world of organic chemicals. Chemists see it not just as a complex name, but as a valuable compound for research and manufacturing. This compound brings together a dioxane ring, a bulky tert-butyl group, and functional hydroxymethyl and acetate features. Its detailed molecular formula is C12H22O5. You find this compound under the HS Code 291570, aligning with organic chemicals and their derivatives. Those deep in chemical synthesis or pharmaceutical development know exactly why that structure and its interaction matter, especially when purity and precision drive their results.
Molecular structure’s always at the center of what makes this compound functional. At the core, you see a 1,3-dioxane ring, a backbone known for stability in organic synthesis. The 2-position carries two methyl groups, giving it the "dimethyl" punch. The 4-position marks the acetate substituent, letting researchers introduce protective groups or cleave it predictably. At the 6-position, a hydroxymethyl group helps with solubility and reactivity—something that matters when you move beyond benchtop chemistry toward larger-scale production. The cis-configuration ensures predictable behavior in stereoselective synthesis, controlling downstream product shapes. These features help drive both purity and targeted chemical reactions.
In the real world, chemists handle tert-Butyl (4R-cis)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate most often as a solid. Depending on temperature and storage conditions, it appears as white or off-white flakes, sometimes a crystalline powder. Its solid state aids in accurate weighing and reduces the risk of accidental spills during transfer and mix-down processes. When exposed to warmth, it may soften, which highlights the need for climate control in storage rooms. Density stands at about 1.07 g/cm³, a value most glass vials can manage without stress. No strong odor drifts off the material, so lab air remains clean during standard use.
Lab staff appreciate a stable material. tert-Butyl (4R-cis)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate does not break down quickly when exposed to light, but it fares best inside amber glass or opaque containers. Slightly soluble in polar solvents like methanol or ethanol, its limited water compatibility adds to its controlled usage. Reactions involving this molecule rely on its protected alcohol and acetate groups, which let synthetic chemists construct larger, more complex molecules step-by-step. The compound takes heat up to about 110°C before showing visible melting, which often lets users dry it via mild vacuum without degradation. Solubility and melting data guide how researchers plan, dissolve, and recover product from reactions.
In the chemical industry, products reach the market only through careful design—this is where tert-Butyl (4R-cis)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate demonstrates value. It serves as a key intermediate for pharmaceuticals and sophisticated materials. Synthetic routes put the tert-butyl-protected dioxane ring front and center, protecting sensitive regions during multi-step reactions. Working with this compound means reliable chain building without losing control over critical functional groups. Manufacturers choose this molecule when purity, precision, and yield all stack up as priorities. Beyond medicine, its dioxane backbone appeals to those building complex fragrances, flavors, or even resins, showing versatility in raw material selection. Sometimes lab purchases focus on this very compound simply for the dependability of its structure, unlocked by well-documented physical and chemical data.
Safety matters everywhere, from the university bench to large-scale plants. Handling tert-Butyl (4R-cis)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate, staff should wear gloves, goggles, and lab coats due to mild but real potential for irritation. The powder, flakes, or crystals can irritate the eyes and lungs if mishandled, just like many organics in a busy lab. Unlike some harsher chemicals, this acetate is neither acutely toxic nor severely hazardous under normal use, but eating or prolonged skin contact should always be avoided. Safety Data Sheets recommend careful disposal and attention when storing near strong acids or oxidizing agents, sidestepping the chance of unexpected breakdown. At worst, heating to decomposition sends organic fumes into the air, so all work belongs in a fume hood.
Nobody in a modern lab wants surprises during mixing or scale-up. Chemists and engineers want predictability, and this compound delivers, owing to its clear melting and boiling information, solubility in chosen solvents, and non-hygroscopic nature. That reliability means less downtime, more consistent yields, and straightforward troubleshooting. Sourcing from a trusted supplier with lot-specific purity data cuts down the risk of impurities, which can ruin entire batches or sidetrack complex synthesis programs. Real-world labs run experiments with backup supplies and tight labeling, because a missed step or mislabeled flask leads to delays—here, simple purity helps keep busy teams on track. Shipments usually arrive in tightly sealed drums or amber glass, with each batch tracked by shipment record and quality signoff. The goal: strong results, high output, and minimized rework.
Behind every pharmaceutical product or specialty material stands a web of raw materials. tert-Butyl (4R-cis)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate keeps its reputation among researchers not just for its synthetic flexibility, but for handling and safety know-how hard-won from years at the bench. Teams care not just about price per kilo, but about safety, traceability, and the way each molecule performs under stress. Factories depend on easy weighing, low volatility, and batch-to-batch reliability, reducing surprise downtime and letting workers maintain safety standards. In the wider conversation on chemical safety and efficiency, products like this acetate hold up in real-world conditions, supported by documentation and end-user experience.
