(9R)-6,7,8,9-Tetrahydro-9-hydroxy-5H-cycloheptapyridin-5-one Hydrochloride carries a complex ring structure with a unique blend of chemical and physical features that demand careful attention in laboratory and industrial environments. This compound emerges in settings that call for specialized materials, particularly where synthetic chemistry and pharmacological interest overlap. People who work with this molecule know its hydrochloride salt form increases its stability and influences solubility. Its increased presence in research signals ongoing demand for reliable, well-characterized raw materials. Chemists often recognize the hydrochloride salt for its safe handling profile compared to free base forms, enhancing its usability across development, testing, and manufacturing.
This compound stands out not only due to its name—imposing by itself—but also through its concrete, measurable characteristics. Looking closely at the appearance, many batches arrive as white or off-white solid, sometimes exhibiting a crystalline powder that reflects its purity and manufacturing route. Density comes in at approximately 1.2 to 1.3 g/cm3, giving it enough substance to be handled as flakes or granules, though powder forms remain the standard. As for the molecular scene, its chemical formula reads C11H13NO2·HCl, and a trained eye can immediately picture the fused cyclohepta and pyridine rings leading to a stable backbone with a single hydroxyl group at the ninth position. The molecular weight centers near 243.7 g/mol, and this specific specification holds weight as every lot must meet defined criteria before use in production cycles or lab work. The hydrochloride salt increases aqueous solubility, and standard practice sees it packaged as a dry solid in tightly sealed containers to avoid deliquescence, as humidity could affect both usability and performance.
Chemicals with ring structures and amide or alcohol groups command smart handling routines. Direct contact calls for gloves and goggles, as accidental contact with eyes or skin may cause irritation, experienced by more than one researcher pushing a rushed schedule. Inhalation risk is moderate—always process powders under a hood or with local exhaust. As with many hydrochloride salts, the compound stays stable at room temperature, yet light, moisture, or prolonged air exposure could compromise product quality, requiring resealing after use. Disposal follows standard hazardous chemical guidelines, never down the sink or in open trash; every milligram counts towards environmental responsibility and regulatory compliance. Even if not formally classified with the most severe hazard labels, respect for chemical handling stays non-negotiable.
In applications from pharmaceutical synthesis to chemical development, (9R)-6,7,8,9-Tetrahydro-9-hydroxy-5H-cycloheptapyridin-5-one Hydrochloride finds its place as a starting material, intermediate, or reference standard. Consistent melting points—often stated in the range of 215–230°C for pure, dry samples—help verify identity at every critical stage. Lot certificates routinely note appearance, purity (usually 98% or higher for research use), moisture by Karl Fischer, and residual solvents, giving every customer actionable information. HS Code assignment eases customs and regulatory hurdles, generally aligning with that of organic chemicals or specialized pharmaceutical intermediates, anchoring international transactions to recognized frameworks. Analytical departments value straightforward solubility and predictable crystal form, which eases process scaling and downstream investigation.
Time in the lab with this molecule teaches a thing or two about practical chemistry. Powders with low-to-moderate static sometimes stick to tools or containers; a quick antistatic spray on spatulas helps reduce losses. When prepping solutions, accuracy in weighing becomes crucial—compound is potent enough that a few milligrams can tip the balance on experimental outcomes. In multi-step organic synthesis, its stable ring system resists unwanted side reactions, but trace moisture or unmatched solvent grade can drive disappointing yields. Teams always store it away from direct sunlight and high humidity, reinforcing longevity and reducing waste. Repeat analytics show clean NMR and HPLC traces for quality product; outliers get investigated without hesitation to protect batch reputation and downstream results.
Managing chemicals that combine complexity and practicality requires more than rote adherence to the protocols. Training every user on the specifics goes beyond what posters and guides offer—a culture of double-checking, careful record-keeping, and shared knowledge keeps errors and waste in check. Building partnerships with suppliers who provide detailed batch documentation, including full spectral analysis and impurity profiles, lays a foundation for trust and reliability. Investing in clean, temperature-stable storage areas pays dividends when dealing with high-value compounds, ensuring every gram counts. Regular safety audits and open dialogue around near-misses help teams preempt problems, not just react. Everyone who handles the material needs to know not just the rules, but why they matter—a lesson learned firsthand in moments of real-world testing.
Sourcing this compound relies on trusted networks that trace back to starting materials like precursor ketones and pyridine derivatives. Certifications documenting the absence of restricted solvents or metals in these raw materials matter to every downstream partner, especially those contributing to pharma or specialty chemical manufacturing. Demand for tight quality control highlights the need for robust supply chains, careful batch tracking, and full transparency around any changes in specification. Industrial users expect clear documentation on purity, form, and safety, not boilerplate, but evidence-backed facts that stand up to inspection and regulatory review. Using compounds like this shapes the wider field's expectations for consistent, high-quality materials, setting benchmarks for what researchers and manufacturers set as non-negotiable in their sourcing standards. Direct experience at the bench, combined with ongoing dialogue with QA and compliance staff, shapes an environment where reliable chemical access supports real progress in research and industry alike.
